What happens to ventricular volume during isovolumetric contraction?

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Recording of left atrial pressure (PLA), left ventricular pressure (PLV), and the rate of change of left ventricular (LV) volume (dV/dt). The early diastolic pressure gradient is generated as LV pressure falls below LA pressure and the late diastolic gradient is generated as atrial contraction increases LA pressure above LV pressure. Data from Little WC, Cheng CP. Left ventricular-arterial coupling in conscious dogs. Am J Physiol 1991;261:H70–H76.

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