Conjunctivitis, which is defined as inflammation of the bulbar and/or palpebral conjunctiva (the transparent lubricating mucous membrane that covers both the surface of the eye and lining of the undersurface of the eyelids), has many etiologies, including infection from various bacteria, fungi, and viruses, as well as toxic and allergic insults. Conjunctivitis, which is also known as pink eye, is common; about 1% of all primary care office visits in the United States are related to conjunctivitis, affecting about 6 million people annually. [1, 2] Show Only about 30% of primary care patients with infectious conjunctivitis are confirmed to have bacterial conjunctivitis, although 80% are treated with antibiotics. [3] The bacterial etiology often depends on geography and age, but the most common include Staphylococcus, Streptococcus, Corynebacterium, Haemophilus, Pseudomonas, and Moraxella species. Complications can range from mild corneal irritation to severe visual loss, which develops in cases caused by extremely pathogenic bacteria, such as Chlamydia trachomatis or Neisseria gonorrhoeae. Bacterial conjunctivitis has been estimated to account for between $377 and $875 million annually in healthcare costs in the United States. [4] Signs and symptoms Signs and symptoms of bacterial conjunctivitis, beyond injected and edematous (inflamed) conjunctiva, include the following:
See Clinical Presentation for more detail. Diagnosis Routine bacterial culture is indicated for specific cases of clinically suspected bacterial disease. These are best obtained with a commercially available sterile red-top culturette using applicators that contain artificial fiber, rather than cotton-tip applicators, which have bacteriostatic properties. Although most routine cases of bacterial conjunctivitis should not require culture confirmation, certain presentations, such as the following, suggest utility to the astute clinician:
Conjunctival scrapings are often used in the diagnosis of bacterial conjunctivitis; they can be collected with topical anesthetic and gentle use of a platinum spatula or similar blunt metallic object. Gram stain is useful for identifying bacterial characteristics, including a rough bacterial titer, a rough estimate of white blood cell (WBC) count, and the presence of chains, clusters, or intracytoplasmic inclusions. Giemsa stain is helpful in screening for intracellular inclusion bodies of Chlamydia. Cultures can be completed for chlamydial and other bacterial organisms, as well as for viral agents. Fungal culture would be unusual except in the setting of a corneal ulcer, a vegetative or gardening injury, or in the case of known contamination of a contact lens solution. The cellular response in conjunctivitis differs according to the cause, as follows:
See Workup for more detail. Management The mainstay of treatment for bacterial conjunctivitis is topical (administered as eye drops or ointment) antibiotic therapy. Systemic antibiotics are indicated for gonorrhea and chlamydial infections. Under certain circumstances, topical antibiotics may be considered of limited benefit and, considering the risks of widespread antibiotic resistance, should be withheld while the disease course resolves without treatment. [5, 6, 7] Steroid use is controversial (see Treatment for more details). Povidone-iodine 1.25% ophthalmic solution may be a safe and viable alternative to topical antibiotics for treating bacterial conjunctivitis, [8] especially in resource-poor countries, where antibiotics may be scarce and/or expensive. A product that contains both povidone iodide 1% and dexamethasone 0.1% is in phase III clinical trials for the treatment of viral and bacterial conjunctivitis (Shire, Dublin, Ireland).
The eye infection conjunctivitis (kun-junk-tih-VY-tus) — often called pinkeye — is common in young kids. It's usually contagious, and breakouts can sweep through preschools and playgrounds. But even teens and adults can get pinkeye. Pinkeye is an inflammation of the conjunctiva, the white part of the eye and the inner eyelids. It's a minor infection and although it might look bad, usually isn't serious. Still, if your child shows signs of pinkeye, it's important to see a doctor. Some kinds of pinkeye go away on their own, but others need treatment.
Infectious pinkeye (the kind that can spread to others) can be caused by many of the bacteria and viruses responsible for colds and other infections — including ear infections, sinus infections, and sore throats. Sometimes it's caused by the same types of bacteria that cause chlamydia and gonorrhea, two sexually transmitted diseases (STDs). Some kinds of pinkeye are noninfectious, such as:
Pinkeye in NewbornsNewborns are at risk for pinkeye and can develop serious health problems if it's not treated. If a pregnant woman has an STD, during delivery the bacteria or virus can pass from the birth canal into the baby's eyes, causing pinkeye. To prevent this, doctors give antibiotic ointment or eye drops to all babies right after birth. Occasionally, this treatment causes a mild chemical conjunctivitis, which usually clears up on its own. Doctors also can screen pregnant women for STDs and treat them during pregnancy to prevent spreading the infection to the baby. What Are the Signs & Symptoms of Pinkeye?Besides the telltale red or pink color that gives pinkeye its name, eye discomfort is a common symptom. Kids might say that it feels like there's sand in the eye. Often, there's some discharge from the eye, and pain and swelling of the conjunctiva. Some kids have swollen eyelids or sensitivity to bright light. Pinkeye can affect one or both eyes. In cases of allergic conjunctivitis, itchiness and watery eyes are common symptoms. Is Pinkeye Contagious?Pinkeye is contagious if it's caused by bacteria or a virus:
Allergic conjunctivitis and irritant conjunctivitis are not contagious. A child can get pinkeye by touching an infected person or something an infected person has touched, such as a used tissue. In the summertime, pinkeye can spread when kids swim in contaminated water or share contaminated towels. It also can spread through coughing and sneezing. Also, someone who has pinkeye in one eye can spread it to the other eye by rubbing or touching the infected eye, then touching the other eye. How Is Pinkeye Diagnosed?If you think your child has pinkeye, it's important to see your health care provider to learn what's causing it and how to treat it. Other serious eye conditions can have similar symptoms, so a child who complains of severe pain, changes in eyesight, swelling around the eyes, or sensitivity to light should be examined. If you can't get an in-person visit, you might be able to do a "video visit" instead. Telehealth — when patients and health care providers use technology for the remote diagnosis and treatment of some health conditions — is becoming more and more popular. Ask your health care provider if his or her practice participates in telemedicine, and check with your insurance provider to see if this option is covered. How Is Pinkeye Treated?Pinkeye caused by a virus usually goes away without any treatment. Pinkeye caused by bacteria is treated with antibiotic eye drops or ointment.
It can be hard to get kids to tolerate eye drops several times a day. If you're having trouble, put the drops on the inner corner of your child's closed eye — when your child opens the eye, the medicine will flow into it. If you still have trouble with drops, ask the doctor about antibiotic ointment, which can be placed in a thin layer where the eyelids meet, and will melt and enter the eye. If your child has allergic conjunctivitis, your doctor may prescribe anti-allergy medicine, either as pills, liquid, or eye drops. You also can give acetaminophen or ibuprofen to relieve discomfort (check instructions for correct amount). How Can Parents Help?Using cool or warm compresses on the eyes may make your child more comfortable. Clean the edges of the infected eye carefully with warm water and gauze or cotton balls. This can also remove the crusts of dried discharge that make the eyelids stick together in the morning. If your child wears contact lenses, your doctor or eye doctor may recommend that the lenses not be worn until the infection is gone. Then, disinfect the lenses and their storage case at least twice before letting your child wear them again. If your child wears disposable contact lenses, throw away the current pair and use a new pair after the infection is gone. Doctors usually recommend keeping kids with contagious conjunctivitis out of school, childcare, or summer camp for a short time. Can Pinkeye Be Prevented?Infectious conjunctivitis is highly contagious, so teach kids to wash their hands well and often with warm water and soap. They also should not share eye drops, tissues, eye makeup, washcloths, towels, or pillowcases. Be sure to wash your own hands well after touching an infected child's eyes, and throw away items like gauze or cotton balls after they've been used. Wash towels and other linens that the child has used in hot water separately from the rest of the family's laundry to avoid contamination. If you know your child is prone to allergic conjunctivitis, keep windows and doors closed on days when the pollen is heavy, and dust and vacuum often to limit allergy triggers. Irritant conjunctivitis can only be prevented by avoiding the irritating causes. Screening and treating pregnant women for STDs can prevent many cases of pinkeye in newborns. A pregnant woman may have bacteria in her birth canal even if she shows no symptoms, which is why prenatal screening is important. When Should I Call the Doctor?If the pinkeye does not improve after 2 to 3 days of treatment, or after a week if untreated, call your doctor. If your child has increased swelling, redness, and tenderness in the eyelids and around the eye, along with a fever, call your doctor. Those symptoms may mean the infection has started to spread beyond the conjunctiva and will need more treatment. |